Tobacco use is associated with increased risk of several cancers, including lung, larynx, oesophagus, oral cavity and pharynx, bladder, pancreas, kidney, liver, stomach, bowel, cervix, leukaemia, and ovarian cancers.

Incidence of some smoking-related cancers is decreasing thanks largely to decreases in smoking prevalence; these include lung cancer (decreasing in males), oesophageal cancer (decreasing in females), and laryngeal cancer. However, unless there is further progress in reducing tobacco exposure, these decreases are expected to slow and eventually stop.

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